If you mean the most dangerous disease as in which kills you the fastest, that would probably be a virus like meningitis, or a bacterial disease like anthrax which can kill you within an day of symptoms onset if untreated.
But more dangerous are probably diseases that we can see but now can’t be treated because of problems such as antibiotic resistance – such as MRSA and VRSA (vancomycin resistant staphlyococcus aureus).
If you mean which disease kills the most people – historically this is the flu, but in the modern era AIDS, cancer and heart disease are the biggest killers in the modern and developed worlds.
Well it’s hard to say what the most dangerous is.
But I know of one disease called Nigleria Fowleri. It lives in warm lakes, like the ones found here in Florida. When you swim, it can go up your nose and into your brain! If that happens, there’s a 95% chance of dying! So it’s very hard to cure and very dangerous!!!
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